Edwin K Jackson Selected Research

Mercaptoethanol (2 Mercaptoethanol)

1/2019	2-Methoxyestradiol Attenuates Angiotensin II-Induced Hypertension, Cardiovascular Remodeling, and Renal Injury.
3/2016	2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism.
12/2015	2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.
11/2010	Candidate genes and mechanisms for 2-methoxyestradiol-mediated vasoprotection.
10/2009	Potential vascular actions of 2-methoxyestradiol.
1/2007	2-Methoxyestradiol and 2-ethoxyestradiol retard the progression of renal disease in aged, obese, diabetic ZSF1 rats.
8/2006	2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle.

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Edwin K Jackson Research Topics

Disease

22	Hypertension (High Blood Pressure) 01/2021 - 02/2002
19	Neoplasms (Cancer) 07/2021 - 10/2005
18	Inflammation (Inflammations) 09/2021 - 08/2004
16	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2020 - 03/2004
10	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 04/2002
9	Pulmonary Hypertension 12/2019 - 10/2005
8	Vascular Remodeling 10/2020 - 02/2002
8	Hypoxia (Hypoxemia) 03/2015 - 03/2004
7	Fibrosis (Cirrhosis) 01/2021 - 01/2007
7	Ischemia 01/2018 - 01/2006
6	Proteinuria 01/2019 - 04/2002
6	Brain Injuries (Brain Injury) 01/2019 - 03/2004
5	Squamous Cell Carcinoma of Head and Neck 06/2020 - 10/2009
5	Hypertrophy 01/2018 - 04/2004
4	No-Reflow Phenomenon 01/2021 - 11/2007
4	Head and Neck Neoplasms (Head and Neck Cancer) 11/2020 - 08/2017
4	Pulmonary Arterial Hypertension 12/2019 - 12/2006
3	Reperfusion Injury 01/2021 - 11/2012
3	Heart Failure 01/2021 - 05/2007
3	Neointima 01/2020 - 08/2006
3	Hyperplasia 01/2020 - 01/2015
3	Infections 01/2020 - 06/2013
3	Sepsis (Septicemia) 01/2020 - 03/2003
3	Cardiomegaly (Heart Hypertrophy) 01/2019 - 04/2008
3	Obesity 01/2018 - 11/2002
3	Kidney Diseases (Kidney Disease) 01/2018 - 01/2007
3	Wounds and Injuries (Trauma) 01/2018 - 12/2005
3	Necrosis 01/2018 - 02/2016
3	Seizures (Absence Seizure) 01/2017 - 04/2006
3	Epilepsy (Aura) 04/2016 - 04/2006
3	Heart Arrest (Cardiac Arrest) 11/2013 - 02/2008
3	Hypothermia 04/2012 - 11/2007
3	Vascular System Injuries 11/2010 - 04/2002
3	Myocardial Infarction 01/2008 - 01/2006
3	Glycosuria 01/2007 - 04/2002
2	Breast Neoplasms (Breast Cancer) 12/2021 - 07/2021
2	Disease Progression 06/2020 - 08/2017
2	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 01/2020 - 06/2013
2	Hemolysis 07/2018 - 06/2009
2	Atrophy 01/2018 - 02/2016
2	Vasculitis (Vasculitides) 01/2018 - 02/2016
2	Stroke (Strokes) 01/2018 - 03/2016
2	Acute Kidney Injury (Acute Renal Failure) 01/2017 - 12/2011
2	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 02/2016 - 04/2002
2	Hemorrhagic Shock 03/2015 - 08/2014
2	Melanoma (Melanoma, Malignant) 12/2014 - 01/2011
2	Endotoxemia 09/2014 - 03/2003

Drug/Important Bio-Agent (IBA)

51	Adenosine (Adenocard)FDA LinkGeneric 09/2021 - 03/2004
12	Estradiol (Delestrogen)FDA LinkGeneric 12/2019 - 02/2002
9	2-MethoxyestradiolIBA 12/2019 - 07/2005
7	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 07/2021 - 06/2009
7	Adenosine Monophosphate (AMP)IBA 01/2019 - 07/2012
7	Mercaptoethanol (2 Mercaptoethanol)IBA 01/2019 - 08/2006
7	Purinergic P1 Receptors (Adenosine Receptor)IBA 01/2018 - 08/2006
7	CytokinesIBA 03/2015 - 03/2004
6	Glucose (Dextrose)FDA LinkGeneric 02/2016 - 04/2002
5	Sitagliptin Phosphate (Januvia)FDA Link 01/2021 - 06/2008
5	CollagenIBA 01/2021 - 08/2004
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2006
5	Estrogens (Estrogen)FDA Link 12/2019 - 12/2004
5	Angiotensin IIIBA 01/2019 - 12/2003
5	Proteins (Proteins, Gene)FDA Link 02/2016 - 12/2007
5	Oxygen (Dioxygen)IBA 03/2015 - 02/2008
5	Caffeine (No Doz)FDA LinkGeneric 02/2008 - 04/2002
4	Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)IBA 01/2021 - 10/2010
4	purineIBA 10/2020 - 04/2016
4	Adenosine DeaminaseIBA 07/2018 - 06/2009
4	CholesterolIBA 11/2010 - 04/2002
4	MonocrotalineIBA 11/2010 - 10/2005
3	Adenosine Triphosphate (ATP)IBA 07/2021 - 09/2010
3	Dipeptidyl-Peptidase IV InhibitorsIBA 10/2018 - 01/2015
3	PurinesIBA 07/2018 - 06/2013
3	Inosine FDA Link 07/2018 - 07/2012
3	EnzymesIBA 01/2017 - 11/2012
3	2',3'-Cyclic-Nucleotide Phosphodiesterases (2',3' Cyclic Nucleotide Phosphodiesterase)IBA 01/2017 - 07/2012
3	Biological ProductsIBA 06/2009 - 02/2002
3	Triglycerides (Triacylglycerol)IBA 01/2007 - 04/2002
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2007 - 03/2004
3	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2007 - 10/2005
2	Estrogen ReceptorsIBA 12/2021 - 11/2002
2	Biomarkers (Surrogate Marker)IBA 11/2020 - 09/2004
2	Adenosine A2B ReceptorIBA 11/2020 - 11/2012
2	2-Chloroadenosine (2 Chloroadenosine)IBA 01/2020 - 12/2015
2	CaspasesIBA 01/2020 - 03/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 09/2004
2	Gonadal Steroid Hormones (Sex Hormones)IBA 12/2019 - 02/2002
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2019 - 04/2008
2	GuanosineIBA 07/2018 - 09/2014
2	SaltsIBA 01/2018 - 12/2016
2	Captopril (Capoten)FDA LinkGeneric 01/2018 - 12/2003
2	AntigensIBA 10/2017 - 12/2014
2	Therapeutic UsesIBA 03/2016 - 11/2010
2	CatecholaminesIBA 01/2015 - 01/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2014 - 05/2007
2	SilverIBA 06/2013 - 06/2011

Therapy/Procedure

15	Therapeutics 11/2020 - 12/2004
5	Immunotherapy 10/2017 - 08/2006
4	Resuscitation 02/2015 - 02/2008
3	Percutaneous Coronary Intervention 01/2021 - 01/2008
3	Ovariectomy (Oophorectomy) 11/2010 - 12/2006